BindingDB PrimarySearch

Found 9 hits of ic50 for monomerid = 50000714
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
Schering-Plough Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity for inhibition of [3H]PAF receptor binding to washed human platelet membranes.				Bioorg Med Chem Lett 2: 597-602 (1992) Article DOI: 10.1016/S0960-894X(01)81205-1 BindingDB Entry DOI: 10.7270/Q2CF9QK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach & Cía, S.A. Curated by ChEMBL					Assay Description Inhibition of PAF-induced platelet aggregation				J Med Chem 36: 2984-97 (1993) BindingDB Entry DOI: 10.7270/Q2ZS2VKZ
J. Uriach & Cía, S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
J. Uriach& C£a.S.A. Curated by ChEMBL					Assay Description Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.				J Med Chem 35: 4118-34 (1992) BindingDB Entry DOI: 10.7270/Q228087F
J. Uriach& C£a.S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Displacement of [3H]-PAF from PAF receptor of human platelet membranes				J Med Chem 41: 1970-9 (1998) Article DOI: 10.1021/jm980046r BindingDB Entry DOI: 10.7270/Q2PV6JH2
University of Virginia Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
Pfizer Central Research Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description PAF-antagonist activity determined in dog platelets by PAF-binding assay				J Med Chem 34: 1209-21 (1991) BindingDB Entry DOI: 10.7270/Q23X85M1
Roche Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.				J Med Chem 34: 1440-6 (1991) BindingDB Entry DOI: 10.7270/Q2BG2MZ9
Roche Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50000714 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Inhibition of [3H]-PAF binding to dog platelets.				J Med Chem 32: 1820-35 (1989) BindingDB Entry DOI: 10.7270/Q2NZ86MR
Roche Research Center Curated by ChEMBL					More data for this Ligand-Target Pair