Compile Data Set for Download or QSAR

Found 9 hits of ic50 for monomerid = 50009341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase FAP (Mus musculus (Mouse))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Mus musculus (Mouse))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry				J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.91E+4	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of recombinant human PREP purified from Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate by spectrophotometry				J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of DPP2 purified from human seminal plasma using Lys-Ala-p-nitroanilide as substrate by spectrophotometry				J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of DPP4 purified from human seminal plasma using Gly-Pro-p-nitroanilide as substrate by spectrophotometry				J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50009341 (CHEMBL3233560 | US9346814, Cmpd No 16 Example 20) Show SMILES O=C(CNC(=O)c1ccnc(c1)-c1ccc(cc1)C#N)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H17N5O2/c21-11-14-3-5-15(6-4-14)18-10-16(7-8-23-18)20(27)24-13-19(26)25-9-1-2-17(25)12-22/h3-8,10,17H,1-2,9,13H2,(H,24,27)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
					More data for this Ligand-Target Pair