Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50017110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50017110 (4-(4-Butoxy-3-methoxy-phenyl)-pyrrolidin-2-one | C...) Show SMILES CCCCOc1ccc(cc1OC)C1CNC(=O)C1 Show InChI InChI=1S/C15H21NO3/c1-3-4-7-19-13-6-5-11(8-14(13)18-2)12-9-15(17)16-10-12/h5-6,8,12H,3-4,7,9-10H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Neurochimie du CNRS Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP for cGMP-PDE.				J Med Chem 32: 1450-7 (1989) BindingDB Entry DOI: 10.7270/Q2DN441H
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50017110 (4-(4-Butoxy-3-methoxy-phenyl)-pyrrolidin-2-one | C...) Show SMILES CCCCOc1ccc(cc1OC)C1CNC(=O)C1 Show InChI InChI=1S/C15H21NO3/c1-3-4-7-19-13-6-5-11(8-14(13)18-2)12-9-15(17)16-10-12/h5-6,8,12H,3-4,7,9-10H2,1-2H3,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Neurochimie du CNRS Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.				J Med Chem 32: 1450-7 (1989) BindingDB Entry DOI: 10.7270/Q2DN441H
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B (Bos taurus-BOVINE)	BDBM50017110 (4-(4-Butoxy-3-methoxy-phenyl)-pyrrolidin-2-one | C...) Show SMILES CCCCOc1ccc(cc1OC)C1CNC(=O)C1 Show InChI InChI=1S/C15H21NO3/c1-3-4-7-19-13-6-5-11(8-14(13)18-2)12-9-15(17)16-10-12/h5-6,8,12H,3-4,7,9-10H2,1-2H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Neurochimie du CNRS Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and calmodu...				J Med Chem 32: 1450-7 (1989) BindingDB Entry DOI: 10.7270/Q2DN441H
					More data for this Ligand-Target Pair