BindingDB PrimarySearch

Found 9 hits of ic50 for monomerid = 50026220
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
High affinity choline transporter 1 (Mus musculus)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT				J Med Chem 29: 376-80 (1986) BindingDB Entry DOI: 10.7270/Q2CJ8CHV
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Mus musculus)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes				Biochem Biophys Res Commun 296: 644-50 (2002) BindingDB Entry DOI: 10.7270/Q2P84D6R
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 2 (RAT)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.59E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 100 uM) in Xenopus laevis oocytes				Biochim Biophys Acta 1417: 224-31 (1999) BindingDB Entry DOI: 10.7270/Q2WS8VJ5
Kyoto University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 2 (Mus musculus)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in Xenopus laevis oocytes				Biochem Biophys Res Commun 296: 644-50 (2002) BindingDB Entry DOI: 10.7270/Q2P84D6R
Kyushu University Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 100 uM) in Xenopus laevis oocytes				Biochim Biophys Acta 1417: 224-31 (1999) BindingDB Entry DOI: 10.7270/Q2WS8VJ5
Kyoto University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 2 (RAT)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.45E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 50 uM) in OCT2-expressing MDCK cells				Pharm Res 18: 1528-34 (2001) BindingDB Entry DOI: 10.7270/Q28G8N0T
Kyoto University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (RAT)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.45E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of TEA uptake (TEA: 50 uM) in OCT1-expressing MDCK cells				Pharm Res 18: 1528-34 (2001) BindingDB Entry DOI: 10.7270/Q28G8N0T
Kyoto University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.01E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibitory activity against Acetylcholinesterase				J Med Chem 39: 5064-71 (1997) Article DOI: 10.1021/jm950771r BindingDB Entry DOI: 10.7270/Q2PZ59GC
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50026220 (2-hydroxy-N,N,N-trimethylethanaminium \| CHEMBL2824...) Show SMILES C[N+](C)(C)CCO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	3.01E+6	n/a	n/a	n/a	n/a	n/a	n/a
Harvard University Curated by ChEMBL					Assay Description Inhibition acetylcholinesterase (AChE) enzyme.				J Med Chem 40: 4360-71 (1998) Article DOI: 10.1021/jm970488n BindingDB Entry DOI: 10.7270/Q2BZ6784
Harvard University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)