Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50028058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50028058 (CHEMBL3338861) Show SMILES COc1ccc(CNC(=O)c2cc(ncc2N2CCOCC2)-c2cncc(C)c2)nc1OC Show InChI InChI=1S/C24H27N5O4/c1-16-10-17(13-25-12-16)20-11-19(21(15-26-20)29-6-8-33-9-7-29)23(30)27-14-18-4-5-22(31-2)24(28-18)32-3/h4-5,10-13,15H,6-9,14H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human OX2R expressed in CHO cells assessed as inhibition of Ala-6,12-orexinA-induced effect after 5 mins by FLIPR assay				Bioorg Med Chem Lett 24: 4884-90 (2014) Article DOI: 10.1016/j.bmcl.2014.08.041 BindingDB Entry DOI: 10.7270/Q2GX4D4J
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50028058 (CHEMBL3338861) Show SMILES COc1ccc(CNC(=O)c2cc(ncc2N2CCOCC2)-c2cncc(C)c2)nc1OC Show InChI InChI=1S/C24H27N5O4/c1-16-10-17(13-25-12-16)20-11-19(21(15-26-20)29-6-8-33-9-7-29)23(30)27-14-18-4-5-22(31-2)24(28-18)32-3/h4-5,10-13,15H,6-9,14H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human OX1R I408V mutant expressed in CHO cells assessed as inhibition of Ala-6,12-orexinA-induced effect after 5 mins by FLIPR...				Bioorg Med Chem Lett 24: 4884-90 (2014) Article DOI: 10.1016/j.bmcl.2014.08.041 BindingDB Entry DOI: 10.7270/Q2GX4D4J
					More data for this Ligand-Target Pair