Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50029426 (CHEMBL24675 | [2-(3,4-Dimethoxy-phenyl)-ethyl]-[4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus) | BDBM50029426 (CHEMBL24675 | [2-(3,4-Dimethoxy-phenyl)-ethyl]-[4-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Displacement of [3H]nitrendipine from calcium channel receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2F47RB8 | |||||||||||
More data for this Ligand-Target Pair |