Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50030630 ((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia Curated by ChEMBL | Assay Description Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M Concentration | J Med Chem 38: 3717-9 (1995) BindingDB Entry DOI: 10.7270/Q2V123TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50030630 ((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 2.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co... | Bioorg Med Chem Lett 7: 2777-2780 (1997) Article DOI: 10.1016/S0960-894X(97)10071-3 BindingDB Entry DOI: 10.7270/Q25Q4W4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50030630 ((RS)-1-aminoindan-1,5-dicarboxylic acid | 1-Amino-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration of the compound for half maximal inhibition of PI hydrolysis (mGluR1a) | J Med Chem 39: 3998-4006 (1996) Article DOI: 10.1021/jm9601718 BindingDB Entry DOI: 10.7270/Q2765DFJ | |||||||||||
More data for this Ligand-Target Pair |