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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50032602   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A


(Homo sapiens (Human))
BDBM50032602
PNG
(CHEMBL3354173)
Show SMILES CCn1c(NC2CCCC2)nc2c(CCc3cccnc3)csc2c1=O
Show InChI InChI=1S/C20H24N4OS/c1-2-24-19(25)18-17(23-20(24)22-16-7-3-4-8-16)15(13-26-18)10-9-14-6-5-11-21-12-14/h5-6,11-13,16H,2-4,7-10H2,1H3,(H,22,23)
PDB
MMDB

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UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.30n/an/an/an/an/an/a



Kyoto 607-8042

Curated by ChEMBL


Assay Description
Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting


J Med Chem 57: 9844-54 (2014)


Article DOI: 10.1021/jm5008215
BindingDB Entry DOI: 10.7270/Q228096D
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50032602
PNG
(CHEMBL3354173)
Show SMILES CCn1c(NC2CCCC2)nc2c(CCc3cccnc3)csc2c1=O
Show InChI InChI=1S/C20H24N4OS/c1-2-24-19(25)18-17(23-20(24)22-16-7-3-4-8-16)15(13-26-18)10-9-14-6-5-11-21-12-14/h5-6,11-13,16H,2-4,7-10H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Kyoto 607-8042

Curated by ChEMBL


Assay Description
Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting


J Med Chem 57: 9844-54 (2014)


Article DOI: 10.1021/jm5008215
BindingDB Entry DOI: 10.7270/Q228096D
More data for this
Ligand-Target Pair