Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Oryctolagus cuniculus) | BDBM50035612 (CHEMBL96926 | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Inhibition of rabbit sarcoplasmic reticulum calcium ATPase by ATP regeneration assay | Bioorg Med Chem 18: 5634-46 (2010) Article DOI: 10.1016/j.bmc.2010.06.032 BindingDB Entry DOI: 10.7270/Q2RB74VD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Oryctolagus cuniculus) | BDBM50035612 (CHEMBL96926 | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rabbit skeletal muscle SERCA1 assessed as reduction in calcium uptake preincubated for 10 mins followed by ATP addition and measured af... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01449 BindingDB Entry DOI: 10.7270/Q2M0493S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |