BindingDB PrimarySearch

Found 7 hits of ic50 for monomerid = 50042874
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Deoxyhypusine hydroxylase (Homo sapiens)	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of DOHH (unknown origin)				Eur J Med Chem 165: 172-197 (2019) Article DOI: 10.1016/j.ejmech.2019.01.018 BindingDB Entry DOI: 10.7270/Q2474F96
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
Zeneca Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs				J Med Chem 55: 8164-77 (2012) Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin \| 2,2'-bipyridine \| 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+8	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferase				Bioorg Med Chem Lett 13: 1523-6 (2003) BindingDB Entry DOI: 10.7270/Q2QZ29BR
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair