Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50049146 (CHEMBL3315251 | US11401286, Example 36) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
Northern Illinois University Curated by ChEMBL | Assay Description Inhibition of human PDE4B | Bioorg Med Chem Lett 24: 4031-4 (2014) Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D] (Homo sapiens (Human)) | BDBM50049146 (CHEMBL3315251 | US11401286, Example 36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MXV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50049146 (CHEMBL3315251 | US11401286, Example 36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MXV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D] (Homo sapiens (Human)) | BDBM50049146 (CHEMBL3315251 | US11401286, Example 36) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MXV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50049146 (CHEMBL3315251 | US11401286, Example 36) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northern Illinois University Curated by ChEMBL | Assay Description Inhibition of human PDE4D | Bioorg Med Chem Lett 24: 4031-4 (2014) Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |