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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50052350   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Squalene synthase


(Rattus norvegicus)		BDBM50052350
PNG
(3-((E)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...)
Show SMILES C1CN2CCC1C(C2)\C=C\c1ccc(cc1)-c1ccccc1 |THB:8:6:4.3:0.1,(9.53,-12.11,;9.74,-13.61,;11.4,-12.88,;11.68,-10.82,;11.12,-9.57,;11.12,-11.41,;12.6,-12.04,;12.88,-13.58,;13.78,-11.1,;15.21,-11.68,;16.43,-10.72,;16.11,-9.22,;17.24,-8.17,;18.7,-8.65,;19.05,-10.15,;17.9,-11.17,;19.85,-7.61,;19.53,-6.11,;20.65,-5.07,;22.14,-5.54,;22.47,-7.04,;21.32,-8.09,)|
Show InChI InChI=1S/C21H23N/c1-2-4-18(5-3-1)19-9-6-17(7-10-19)8-11-21-16-22-14-12-20(21)13-15-22/h1-11,20-21H,12-16H2/b11-8+
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MMDB

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Similars
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Zeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibition against rat microsomal squalene synthase (SS)

J Med Chem 39: 2971-9 (1996)


Article DOI: 10.1021/jm950907l
BindingDB Entry DOI: 10.7270/Q24J0D7G
More data for this
Ligand-Target Pair