Found 2 hits of ic50 for monomerid = 50059870 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50059870
((R)-2-({4-[((R)-2-Amino-3-mercapto-propylamino)-me...)Show SMILES CSC[C@H](NC(=O)c1cc(CNC[C@@H](N)CS)ccc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C21H27N3O3S2/c1-29-13-19(21(26)27)24-20(25)18-9-14(10-23-11-16(22)12-28)7-8-17(18)15-5-3-2-4-6-15/h2-9,16,19,23,28H,10-13,22H2,1H3,(H,24,25)(H,26,27)/t16-,19+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Activity against human Farnesyltransferase |
J Med Chem 40: 2971-90 (1997)
Article DOI: 10.1021/jm970226l BindingDB Entry DOI: 10.7270/Q26M37HF |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50059870
((R)-2-({4-[((R)-2-Amino-3-mercapto-propylamino)-me...)Show SMILES CSC[C@H](NC(=O)c1cc(CNC[C@@H](N)CS)ccc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C21H27N3O3S2/c1-29-13-19(21(26)27)24-20(25)18-9-14(10-23-11-16(22)12-28)7-8-17(18)15-5-3-2-4-6-15/h2-9,16,19,23,28H,10-13,22H2,1H3,(H,24,25)(H,26,27)/t16-,19+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Activity against Geranylgeranyl transferase type I |
J Med Chem 40: 2971-90 (1997)
Article DOI: 10.1021/jm970226l BindingDB Entry DOI: 10.7270/Q26M37HF |
More data for this Ligand-Target Pair | |