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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50061449   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dimer of Protein farnesyltransferase subunit beta


(Homo sapiens (Human))
BDBM50061449
PNG
(1-[5-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro...)
Show SMILES Clc1ccc2SC(Cn3ccnc3)C(OCc3ccc(Cl)cc3Cl)c2c1
Show InChI InChI=1S/C19H15Cl3N2OS/c20-13-3-4-17-15(7-13)19(18(26-17)9-24-6-5-23-11-24)25-10-12-1-2-14(21)8-16(12)22/h1-8,11,18-19H,9-10H2
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human farnesyltransferase


J Med Chem 40: 4103-12 (1998)


Article DOI: 10.1021/jm970291v
BindingDB Entry DOI: 10.7270/Q2T152R0
More data for this
Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))
BDBM50061449
PNG
(1-[5-Chloro-3-(2,4-dichloro-benzyloxy)-2,3-dihydro...)
Show SMILES Clc1ccc2SC(Cn3ccnc3)C(OCc3ccc(Cl)cc3Cl)c2c1
Show InChI InChI=1S/C19H15Cl3N2OS/c20-13-3-4-17-15(7-13)19(18(26-17)9-24-6-5-23-11-24)25-10-12-1-2-14(21)8-16(12)22/h1-8,11,18-19H,9-10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity against Geranylgeranyl transferase type I


J Med Chem 40: 4103-12 (1998)


Article DOI: 10.1021/jm970291v
BindingDB Entry DOI: 10.7270/Q2T152R0
More data for this
Ligand-Target Pair