Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50074501 (Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
South Dakota State University Curated by ChEMBL | Assay Description Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting method | Eur J Med Chem 138: 900-908 (2017) Article DOI: 10.1016/j.ejmech.2017.07.016 BindingDB Entry DOI: 10.7270/Q2R78HRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50074501 (Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
South Dakota State University Curated by ChEMBL | Assay Description Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi... | Eur J Med Chem 78: 1-9 (2014) Article DOI: 10.1016/j.ejmech.2014.03.040 BindingDB Entry DOI: 10.7270/Q2VD710K | |||||||||||
More data for this Ligand-Target Pair |