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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50090686   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50090686
PNG
(2-Methyl-7-phenyl-[1,8]naphthyridine | 2-methyl-7-...)
Show SMILES Cc1ccc2ccc(nc2n1)-c1ccccc1
Show InChI InChI=1S/C15H12N2/c1-11-7-8-13-9-10-14(17-15(13)16-11)12-5-3-2-4-6-12/h2-10H,1H3
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MMDB

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Article
PubMed
n/an/a 664n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization

Bioorg Med Chem Lett 17: 6525-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.083
BindingDB Entry DOI: 10.7270/Q2V40TXS
More data for this
Ligand-Target Pair