Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50112382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50112382 (1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...) Show SMILES Fc1ccc(cc1)-c1ccc(Cn2cncc2CN2CCN(C(=O)C2)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C27H24ClFN4O/c28-23-2-1-3-25(14-23)33-13-12-31(18-27(33)34)17-26-15-30-19-32(26)16-20-4-6-21(7-5-20)22-8-10-24(29)11-9-22/h1-11,14-15,19H,12-13,16-18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.				Bioorg Med Chem Lett 12: 1269-73 (2002) BindingDB Entry DOI: 10.7270/Q2T72GSB
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50112382 (1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...) Show SMILES Fc1ccc(cc1)-c1ccc(Cn2cncc2CN2CCN(C(=O)C2)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C27H24ClFN4O/c28-23-2-1-3-25(14-23)33-13-12-31(18-27(33)34)17-26-15-30-19-32(26)16-20-4-6-21(7-5-20)22-8-10-24(29)11-9-22/h1-11,14-15,19H,12-13,16-18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]-GGPP into a biotinylated peptide corresponding to the C-ter...				Bioorg Med Chem Lett 12: 1269-73 (2002) BindingDB Entry DOI: 10.7270/Q2T72GSB
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50112382 (1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...) Show SMILES Fc1ccc(cc1)-c1ccc(Cn2cncc2CN2CCN(C(=O)C2)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C27H24ClFN4O/c28-23-2-1-3-25(14-23)33-13-12-31(18-27(33)34)17-26-15-30-19-32(26)16-20-4-6-21(7-5-20)22-8-10-24(29)11-9-22/h1-11,14-15,19H,12-13,16-18H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]-GGPP into a biotinylated peptide corresponding to the C-ter...				Bioorg Med Chem Lett 12: 1269-73 (2002) BindingDB Entry DOI: 10.7270/Q2T72GSB
					More data for this Ligand-Target Pair