Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against human Coagulation factor X | Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against coagulation factor Xa | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against coagulation factor Xa | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against trypsin | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against thrombin | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K-dependent protein C (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against activated protein C | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-1 (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against kallikrein | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50114436 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against tissue plasminogen activator | Bioorg Med Chem Lett 12: 1651-5 (2002) BindingDB Entry DOI: 10.7270/Q2VT1RFZ | |||||||||||
More data for this Ligand-Target Pair |