Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50115924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50115924 (4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...) Show SMILES Cc1ccccc1COC(=O)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1 Show InChI InChI=1S/C25H27N5O2/c1-20-4-2-3-5-23(20)18-32-25(31)29-12-10-28(11-13-29)17-24-15-27-19-30(24)16-22-8-6-21(14-26)7-9-22/h2-9,15,19H,10-13,16-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitor of Farnesyl protein transferase(FTPase) required to reduce radiolabel [1-3H] incorporation by 50%				Bioorg Med Chem Lett 12: 2027-30 (2002) BindingDB Entry DOI: 10.7270/Q2TQ60VS
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50115924 (4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...) Show SMILES Cc1ccccc1COC(=O)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1 Show InChI InChI=1S/C25H27N5O2/c1-20-4-2-3-5-23(20)18-32-25(31)29-12-10-28(11-13-29)17-24-15-27-19-30(24)16-22-8-6-21(14-26)7-9-22/h2-9,15,19H,10-13,16-18H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATP				Bioorg Med Chem Lett 12: 2027-30 (2002) BindingDB Entry DOI: 10.7270/Q2TQ60VS
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50115924 (4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...) Show SMILES Cc1ccccc1COC(=O)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1 Show InChI InChI=1S/C25H27N5O2/c1-20-4-2-3-5-23(20)18-32-25(31)29-12-10-28(11-13-29)17-24-15-27-19-30(24)16-22-8-6-21(14-26)7-9-22/h2-9,15,19H,10-13,16-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description The concentration required to displace 50% of a highly potent radiolabeled FPTase inhibitor				Bioorg Med Chem Lett 12: 2027-30 (2002) BindingDB Entry DOI: 10.7270/Q2TQ60VS
					More data for this Ligand-Target Pair