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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50116025   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Mus musculus (mouse))		BDBM50116025
PNG
(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1c(F)c(F)nc(F)c1F
Show InChI InChI=1S/C19H9F5N4/c20-11-3-1-9(2-4-11)15-16(10-5-7-25-8-6-10)27-19(26-15)12-13(21)17(23)28-18(24)14(12)22/h1-8H,(H,26,27)
PDB
MMDB

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KEGG

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n/an/a 90n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATP

Bioorg Med Chem Lett 12: 2109-12 (2002)


BindingDB Entry DOI: 10.7270/Q2610ZNX
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50116025
PNG
(2,3,5,6-Tetrafluoro-4-[4-(4-fluoro-phenyl)-5-pyrid...)
Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1c(F)c(F)nc(F)c1F
Show InChI InChI=1S/C19H9F5N4/c20-11-3-1-9(2-4-11)15-16(10-5-7-25-8-6-10)27-19(26-15)12-13(21)17(23)28-18(24)14(12)22/h1-8H,(H,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIA

Bioorg Med Chem Lett 12: 2109-12 (2002)


BindingDB Entry DOI: 10.7270/Q2610ZNX
More data for this
Ligand-Target Pair