Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystine/glutamate transporter (Homo sapiens (Human)) | BDBM50126155 (CHEMBL3629578) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University Curated by ChEMBL | Assay Description Inhibition of Xct in human CCF-STTG1 cells assessed as glutamate release after 2 hrs by fluorometry | Bioorg Med Chem Lett 25: 4787-92 (2015) Article DOI: 10.1016/j.bmcl.2015.07.018 BindingDB Entry DOI: 10.7270/Q27H1MD5 | |||||||||||
More data for this Ligand-Target Pair |