Found 4 hits of ic50 for monomerid = 50130514 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130514
(CHEMBL3634324)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)c1cccc2NC(=O)CCc12 Show InChI InChI=1S/C30H32N2O4/c33-23(20-36-28-12-5-4-9-26(28)30(35)22-7-2-1-3-8-22)19-32-17-15-21(16-18-32)24-10-6-11-27-25(24)13-14-29(34)31-27/h1-12,21,23,33H,13-20H2,(H,31,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130514
(CHEMBL3634324)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)c1cccc2NC(=O)CCc12 Show InChI InChI=1S/C30H32N2O4/c33-23(20-36-28-12-5-4-9-26(28)30(35)22-7-2-1-3-8-22)19-32-17-15-21(16-18-32)24-10-6-11-27-25(24)13-14-29(34)31-27/h1-12,21,23,33H,13-20H2,(H,31,34) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130514
(CHEMBL3634324)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)c1cccc2NC(=O)CCc12 Show InChI InChI=1S/C30H32N2O4/c33-23(20-36-28-12-5-4-9-26(28)30(35)22-7-2-1-3-8-22)19-32-17-15-21(16-18-32)24-10-6-11-27-25(24)13-14-29(34)31-27/h1-12,21,23,33H,13-20H2,(H,31,34) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130514
(CHEMBL3634324)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)c1cccc2NC(=O)CCc12 Show InChI InChI=1S/C30H32N2O4/c33-23(20-36-28-12-5-4-9-26(28)30(35)22-7-2-1-3-8-22)19-32-17-15-21(16-18-32)24-10-6-11-27-25(24)13-14-29(34)31-27/h1-12,21,23,33H,13-20H2,(H,31,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |