Found 4 hits of ic50 for monomerid = 50130529 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130529
(CHEMBL3634336)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N2Cc3ccccc3C2=O)cc1 Show InChI InChI=1S/C23H28N2O4/c1-28-20-6-8-21(9-7-20)29-16-19(26)15-24-12-10-18(11-13-24)25-14-17-4-2-3-5-22(17)23(25)27/h2-9,18-19,26H,10-16H2,1H3 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130529
(CHEMBL3634336)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N2Cc3ccccc3C2=O)cc1 Show InChI InChI=1S/C23H28N2O4/c1-28-20-6-8-21(9-7-20)29-16-19(26)15-24-12-10-18(11-13-24)25-14-17-4-2-3-5-22(17)23(25)27/h2-9,18-19,26H,10-16H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130529
(CHEMBL3634336)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N2Cc3ccccc3C2=O)cc1 Show InChI InChI=1S/C23H28N2O4/c1-28-20-6-8-21(9-7-20)29-16-19(26)15-24-12-10-18(11-13-24)25-14-17-4-2-3-5-22(17)23(25)27/h2-9,18-19,26H,10-16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130529
(CHEMBL3634336)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N2Cc3ccccc3C2=O)cc1 Show InChI InChI=1S/C23H28N2O4/c1-28-20-6-8-21(9-7-20)29-16-19(26)15-24-12-10-18(11-13-24)25-14-17-4-2-3-5-22(17)23(25)27/h2-9,18-19,26H,10-16H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |