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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50139578   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))
BDBM50139578
PNG
(4-(5-{[3-(2-Chloro-benzyl)-2-oxo-2,3,4,5-tetrahydr...)
Show SMILES Clc1ccccc1CN1CCc2ccccc2C(NCc2cncn2Cc2ccc(cc2)C#N)C1=O
Show InChI InChI=1S/C29H26ClN5O/c30-27-8-4-2-6-24(27)19-34-14-13-23-5-1-3-7-26(23)28(29(34)36)33-17-25-16-32-20-35(25)18-22-11-9-21(15-31)10-12-22/h1-12,16,20,28,33H,13-14,17-19H2
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MMDB

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PubMed
n/an/a 23n/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Inhibition of farnesyltransferase


Bioorg Med Chem Lett 14: 767-71 (2004)


BindingDB Entry DOI: 10.7270/Q2348JSW
More data for this
Ligand-Target Pair