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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50143878   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50143878
PNG
(2-Butoxycarbonylamino-5-[3-(4-carbamimidoyl-phenyl...)
Show SMILES CCCCOC(=O)N[C@@H](CCC(=O)N1CCC2(CC1)N(C)C(=O)N(C2=O)c1ccc(cc1)C(N)=N)C(O)=O
Show InChI InChI=1S/C25H34N6O7/c1-3-4-15-38-23(36)28-18(21(33)34)9-10-19(32)30-13-11-25(12-14-30)22(35)31(24(37)29(25)2)17-7-5-16(6-8-17)20(26)27/h5-8,18H,3-4,9-15H2,1-2H3,(H3,26,27)(H,28,36)(H,33,34)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)


J Med Chem 47: 2037-61 (2004)


Article DOI: 10.1021/jm030354b
BindingDB Entry DOI: 10.7270/Q2FQ9W1H
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50143878
PNG
(2-Butoxycarbonylamino-5-[3-(4-carbamimidoyl-phenyl...)
Show SMILES CCCCOC(=O)N[C@@H](CCC(=O)N1CCC2(CC1)N(C)C(=O)N(C2=O)c1ccc(cc1)C(N)=N)C(O)=O
Show InChI InChI=1S/C25H34N6O7/c1-3-4-15-38-23(36)28-18(21(33)34)9-10-19(32)30-13-11-25(12-14-30)22(35)31(24(37)29(25)2)17-7-5-16(6-8-17)20(26)27/h5-8,18H,3-4,9-15H2,1-2H3,(H3,26,27)(H,28,36)(H,33,34)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 65n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)


J Med Chem 47: 2037-61 (2004)


Article DOI: 10.1021/jm030354b
BindingDB Entry DOI: 10.7270/Q2FQ9W1H
More data for this
Ligand-Target Pair