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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50148531   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidase 1


(Homo sapiens (Human))
BDBM50148531
PNG
(2-[(1-Amino-2-cyclohexyl-ethyl)-hydroxy-phosphinoy...)
Show SMILES OC(=O)C(Cc1ccc(I)cc1)CP(O)(=O)C(=N)CC1CCCCC1
Show InChI InChI=1S/C18H25INO4P/c19-16-8-6-14(7-9-16)10-15(18(21)22)12-25(23,24)17(20)11-13-4-2-1-3-5-13/h6-9,13,15,20H,1-5,10-12H2,(H,21,22)(H,23,24)
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n/an/a 8n/an/an/an/an/an/a



The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Curated by ChEMBL


Assay Description
Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancer


Bioorg Med Chem Lett 14: 3531-3 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.057
BindingDB Entry DOI: 10.7270/Q2GX4B1C
More data for this
Ligand-Target Pair
Dipeptidase 1


(Homo sapiens (Human))
BDBM50148531
PNG
(2-[(1-Amino-2-cyclohexyl-ethyl)-hydroxy-phosphinoy...)
Show SMILES OC(=O)C(Cc1ccc(I)cc1)CP(O)(=O)C(=N)CC1CCCCC1
Show InChI InChI=1S/C18H25INO4P/c19-16-8-6-14(7-9-16)10-15(18(21)22)12-25(23,24)17(20)11-13-4-2-1-3-5-13/h6-9,13,15,20H,1-5,10-12H2,(H,21,22)(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Curated by ChEMBL


Assay Description
Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancer


Bioorg Med Chem Lett 14: 3531-3 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.057
BindingDB Entry DOI: 10.7270/Q2GX4B1C
More data for this
Ligand-Target Pair