Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acid-sensing ion channel 1 (Rattus norvegicus) | BDBM50157090 (6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University Curated by ChEMBL | Assay Description Inhibition of ASIC1a in rat dorsal root ganglion neurons assessed as reduction in peak current preincubated for 120 secs followed by acid medium stim... | Bioorg Med Chem 26: 3158-3165 (2018) Article DOI: 10.1016/j.bmc.2018.04.042 BindingDB Entry DOI: 10.7270/Q2PZ5CBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid-sensing ion channel 3 (Rattus norvegicus) | BDBM50157090 (6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of ASIC3 in rat DRG neurons | J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ | |||||||||||
More data for this Ligand-Target Pair |