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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50158017   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2


(Homo sapiens (Human))		BDBM50158017
PNG
(CHEMBL180384 | N-[13-(5-Chloro-thiophene-2-sulfony...)
Show SMILES Clc1ccc(s1)S(=O)(=O)NC1C2CCC1Cc1cc(NC(=O)CN3CCCCC3)ccc1C2 |THB:17:16:10:13.12,9:10:16.31.15.32:13.12,30:31:10:13.12|
Show InChI InChI=1S/C24H30ClN3O3S2/c25-21-8-9-23(32-21)33(30,31)27-24-17-4-5-18(24)13-19-14-20(7-6-16(19)12-17)26-22(29)15-28-10-2-1-3-11-28/h6-9,14,17-18,24,27H,1-5,10-13,15H2,(H,26,29)
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KEGG

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Similars
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cells

Bioorg Med Chem Lett 15: 373-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.062
BindingDB Entry DOI: 10.7270/Q2445KZQ
More data for this
Ligand-Target Pair