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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50159897   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50159897
PNG
(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-4-methyl-penty...)
Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1Cl
Show InChI InChI=1S/C25H32ClN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)
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PC cid
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Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Organon Laboratories Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration measured by cellular decreases in forskolin stimulated cAMP in CHO cells stably transfected with hORL1 receptor


Bioorg Med Chem Lett 15: 589-93 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.049
BindingDB Entry DOI: 10.7270/Q2K35T50
More data for this
Ligand-Target Pair
Nociceptin receptor


(Homo sapiens (Human))
BDBM50159897
PNG
(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-4-methyl-penty...)
Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1Cl
Show InChI InChI=1S/C25H32ClN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 141n/an/an/an/an/an/a



Organon Laboratories Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration measured by cellular decreases in forskolin stimulated cAMP in CHO cells stably transfected with hORL1 receptor


Bioorg Med Chem Lett 15: 589-93 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.049
BindingDB Entry DOI: 10.7270/Q2K35T50
More data for this
Ligand-Target Pair