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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50165700   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50165700
PNG
(CHEMBL3800127)
Show SMILES CCC[C@H]1N(CCC[C@@]1(Oc1ccc(cc1)C(F)(F)F)C(=O)N1CCC(CC1)Oc1ccc(cn1)C(N)=O)C(=O)c1cnccc1C(F)(F)F |r|
Show InChI InChI=1S/C13H16N2O8/c16-6-9-10(17)11(18)12(19)13(22-9)23-14-5-7-1-3-8(4-2-7)15(20)21/h1-5,9-13,16-19H,6H2
PDB
MMDB

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Article
PubMed
n/an/a 144n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human MDM2 assessed as inhibition of interaction with p53 by fluorescence polarization assay

Bioorg Med Chem Lett 26: 2735-8 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.078
BindingDB Entry DOI: 10.7270/Q28S4RTD
More data for this
Ligand-Target Pair