Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50173846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50173846 (4-(4-benzoylphenylamino)-6-(2-morpholinoethylamino...) Show SMILES O=C(c1ccccc1)c1ccc(Nc2c(cnc3cnc(NCCN4CCOCC4)cc23)C#N)cc1 Show InChI InChI=1S/C28H26N6O2/c29-17-22-18-31-25-19-32-26(30-10-11-34-12-14-36-15-13-34)16-24(25)27(22)33-23-8-6-21(7-9-23)28(35)20-4-2-1-3-5-20/h1-9,16,18-19H,10-15H2,(H,30,32)(H,31,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylation				Bioorg Med Chem Lett 15: 5288-92 (2005) Article DOI: 10.1016/j.bmcl.2005.08.029 BindingDB Entry DOI: 10.7270/Q2JS9Q0M
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