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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50183729   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Disintegrin and metalloproteinase domain-containing protein 17


(Sus scrofa (pig))
BDBM50183729
PNG
(CHEMBL207180 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)
Show SMILES Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC(C)(C)C)CC2)c2ccccc2n1
Show InChI InChI=1S/C30H38N4O4/c1-21-17-23(25-7-5-6-8-26(25)31-21)19-38-24-11-9-22(10-12-24)28(36)32-30(18-27(35)33-37)13-15-34(16-14-30)20-29(2,3)4/h5-12,17,37H,13-16,18-20H2,1-4H3,(H,32,36)(H,33,35)
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Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of porcine TACE


Bioorg Med Chem Lett 16: 2699-704 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.015
BindingDB Entry DOI: 10.7270/Q2TB16H3
More data for this
Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17


(Homo sapiens (Human))
BDBM50183729
PNG
(CHEMBL207180 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)
Show SMILES Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC(C)(C)C)CC2)c2ccccc2n1
Show InChI InChI=1S/C30H38N4O4/c1-21-17-23(25-7-5-6-8-26(25)31-21)19-38-24-11-9-22(10-12-24)28(36)32-30(18-27(35)33-37)13-15-34(16-14-30)20-29(2,3)4/h5-12,17,37H,13-16,18-20H2,1-4H3,(H,32,36)(H,33,35)
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KEGG

UniProtKB/SwissProt

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antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 143n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of LPS-stimulated TNFalpha production in human whole blood


Bioorg Med Chem Lett 16: 2699-704 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.015
BindingDB Entry DOI: 10.7270/Q2TB16H3
More data for this
Ligand-Target Pair