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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50186320   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))
BDBM50186320
PNG
(3-chloro-N-(4-methylthiazol-2-yl)benzamide | CHEMB...)
Show SMILES Cc1csc(NC(=O)c2cccc(Cl)c2)n1
Show InChI InChI=1S/C11H9ClN2OS/c1-7-6-16-11(13-7)14-10(15)8-3-2-4-9(12)5-8/h2-6H,1H3,(H,13,14,15)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 5.49E+3n/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Inhibition of [3H]MPEP binding to mGluR5 in rat brain membrane


Bioorg Med Chem Lett 16: 3371-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.032
BindingDB Entry DOI: 10.7270/Q2RV0N9Z
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50186320
PNG
(3-chloro-N-(4-methylthiazol-2-yl)benzamide | CHEMB...)
Show SMILES Cc1csc(NC(=O)c2cccc(Cl)c2)n1
Show InChI InChI=1S/C11H9ClN2OS/c1-7-6-16-11(13-7)14-10(15)8-3-2-4-9(12)5-8/h2-6H,1H3,(H,13,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Antagonist activity against mGluR5 expressed in CHO cells assessed as inhibition of agonist-induced phosphoinositide hydrolysis


Bioorg Med Chem Lett 16: 3371-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.032
BindingDB Entry DOI: 10.7270/Q2RV0N9Z
More data for this
Ligand-Target Pair