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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50192304   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)
BDBM50192304
PNG
((S)-2-(2-{3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-d...)
Show SMILES C[C@H](NC(=O)Cn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O)C(O)=O |c:30|
Show InChI InChI=1S/C29H50N4O11SSi2/c1-17-13-33(26(38)32(23(17)35)14-21(34)31-18(2)25(36)37)24-22(43-47(11,12)28(6,7)8)29(19(30)16-45(39,40)44-29)20(42-24)15-41-46(9,10)27(3,4)5/h13,16,18,20,22,24H,14-15,30H2,1-12H3,(H,31,34)(H,36,37)/t18-,20+,22-,24+,29+/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



University of Pittsburgh School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activity


J Med Chem 49: 4834-41 (2006)


Article DOI: 10.1021/jm0604575
BindingDB Entry DOI: 10.7270/Q2GH9HKC
More data for this
Ligand-Target Pair
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)
BDBM50192304
PNG
((S)-2-(2-{3-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-d...)
Show SMILES C[C@H](NC(=O)Cn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O)C(O)=O |c:30|
Show InChI InChI=1S/C29H50N4O11SSi2/c1-17-13-33(26(38)32(23(17)35)14-21(34)31-18(2)25(36)37)24-22(43-47(11,12)28(6,7)8)29(19(30)16-45(39,40)44-29)20(42-24)15-41-46(9,10)27(3,4)5/h13,16,18,20,22,24H,14-15,30H2,1-12H3,(H,31,34)(H,36,37)/t18-,20+,22-,24+,29+/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



University of Pittsburgh School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of FLAG-p66/HIS-p51-mediated HIV1 reverse transcriptase dimerization


J Med Chem 49: 4834-41 (2006)


Article DOI: 10.1021/jm0604575
BindingDB Entry DOI: 10.7270/Q2GH9HKC
More data for this
Ligand-Target Pair