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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50207855   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiopoietin-1 receptor


(Homo sapiens (Human))
BDBM50207855
PNG
(CHEMBL245744 | N-(3-isopropylphenyl)-4-methyl-3-(3...)
Show SMILES CNc1ncnc(n1)-c1cccnc1Oc1cc(ccc1C)C(=O)Nc1cccc(c1)C(C)C
Show InChI InChI=1S/C26H26N6O2/c1-16(2)18-7-5-8-20(13-18)31-24(33)19-11-10-17(3)22(14-19)34-25-21(9-6-12-28-25)23-29-15-30-26(27-4)32-23/h5-16H,1-4H3,(H,31,33)(H,27,29,30,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
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PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of Tie2 after 90 mins by HTRF assay


Bioorg Med Chem Lett 17: 2886-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.067
BindingDB Entry DOI: 10.7270/Q2445M4C
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50207855
PNG
(CHEMBL245744 | N-(3-isopropylphenyl)-4-methyl-3-(3...)
Show SMILES CNc1ncnc(n1)-c1cccnc1Oc1cc(ccc1C)C(=O)Nc1cccc(c1)C(C)C
Show InChI InChI=1S/C26H26N6O2/c1-16(2)18-7-5-8-20(13-18)31-24(33)19-11-10-17(3)22(14-19)34-25-21(9-6-12-28-25)23-29-15-30-26(27-4)32-23/h5-16H,1-4H3,(H,31,33)(H,27,29,30,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of KDR after 90 mins by HTRF assay


Bioorg Med Chem Lett 17: 2886-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.067
BindingDB Entry DOI: 10.7270/Q2445M4C
More data for this
Ligand-Target Pair