BindingDB PrimarySearch

Found 8 hits of ic50 for monomerid = 50222360
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as inhibition of fibronectin-mediated cell adhesion after 30 mins by fl...				Eur J Med Chem 83: 284-93 (2014) Article DOI: 10.1016/j.ejmech.2014.06.041 BindingDB Entry DOI: 10.7270/Q2S75HWX
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bologna Curated by ChEMBL					Assay Description Inhibition of integrin alphavbeta3-mediated SK-MEL-24 cell adhesion to fibronectin				Bioorg Med Chem 15: 7380-90 (2007) Article DOI: 10.1016/j.bmc.2007.07.049 BindingDB Entry DOI: 10.7270/Q2N0167H
Università di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK
TBA					More data for this Ligand-Target Pair
Integrin alpha-V/beta-5 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...				Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK
TBA					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at alpha2bbeta3 in human HEL cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...				Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK
TBA					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...				Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK
TBA					More data for this Ligand-Target Pair
Integrin alpha-5/beta-1 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone...				Citation and Details BindingDB Entry DOI: 10.7270/Q2154MPK
TBA					More data for this Ligand-Target Pair
Integrin alpha-5/beta-1 (Homo sapiens (Human))	BDBM50222360 (Ac-Asp-Arg-Leu-Asp-Ser-OH \| CHEMBL238484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.59E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bologna Curated by ChEMBL					Assay Description Inhibition of integrin alpha5beta1-mediated K562 cell adhesion to fibronectin				Bioorg Med Chem 15: 7380-90 (2007) Article DOI: 10.1016/j.bmc.2007.07.049 BindingDB Entry DOI: 10.7270/Q2N0167H
Università di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair