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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50232924   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial


(Homo sapiens (Human))		BDBM50232924
PNG
(CHEMBL4085424)
Show SMILES N[C@@H](CCC(N)=O)C(=O)N1CCC(CC1)Nc1ccc2CN(Cc2c1)S(=O)(=O)c1ccc(O)cc1O |r|
Show InChI InChI=1S/C24H31N5O6S/c25-20(4-6-23(26)32)24(33)28-9-7-17(8-10-28)27-18-2-1-15-13-29(14-16(15)11-18)36(34,35)22-5-3-19(30)12-21(22)31/h1-3,5,11-12,17,20,27,30-31H,4,6-10,13-14,25H2,(H2,26,32)/t20-/m0/s1
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PC cid
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Article
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n/an/a 72n/an/an/an/an/an/a



National Institute of Biological Science

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-SUMO tagged recombinant human PDK2 using [32P]-gamma-ATP assessed as decrease in incorporation of radioactivity into E1...

J Med Chem 60: 1142-1150 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01540
BindingDB Entry DOI: 10.7270/Q2BP0514
More data for this
Ligand-Target Pair