Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 50234094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50234094 (CHEMBL4089715) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1ccccc1C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)8-3-1-2-4-10(8)18-7-5-9(12(16)17)13-6-7;/h1-4,7,9,13H,5-6H2,(H,14,15)(H,16,17);1H/t7-,9+;/m1./s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Antagonist activity at recombinant rat full length GluK1 receptor expressed in HEK293T cells assessed as inhibition of glutamate induced increase in ...				J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50234094 (CHEMBL4089715) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1ccccc1C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)8-3-1-2-4-10(8)18-7-5-9(12(16)17)13-6-7;/h1-4,7,9,13H,5-6H2,(H,14,15)(H,16,17);1H/t7-,9+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Antagonist activity at recombinant rat full length GluK2 receptor expressed in HEK293T cells assessed as inhibition of glutamate induced increase in ...				J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50234094 (CHEMBL4089715) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1ccccc1C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)8-3-1-2-4-10(8)18-7-5-9(12(16)17)13-6-7;/h1-4,7,9,13H,5-6H2,(H,14,15)(H,16,17);1H/t7-,9+;/m1./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...				J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50234094 (CHEMBL4089715) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1ccccc1C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)8-3-1-2-4-10(8)18-7-5-9(12(16)17)13-6-7;/h1-4,7,9,13H,5-6H2,(H,14,15)(H,16,17);1H/t7-,9+;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...				J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50234094 (CHEMBL4089715) Show SMILES Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1ccccc1C(O)=O |r| Show InChI InChI=1S/C12H13NO5.ClH/c14-11(15)8-3-1-2-4-10(8)18-7-5-9(12(16)17)13-6-7;/h1-4,7,9,13H,5-6H2,(H,14,15)(H,16,17);1H/t7-,9+;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake after 15 mins by TopCount scintillation counting metho...				J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ
					More data for this Ligand-Target Pair