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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50235463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Farnesyl pyrophosphate synthase


(Homo sapiens (Human))		BDBM50235463
PNG
(CHEMBL4067698)
Show SMILES COc1cc(C)c(Cl)cc1-c1cc2c(NCP(O)(O)=O)ncnc2s1
Show InChI InChI=1S/C15H15ClN3O4PS/c1-8-3-12(23-2)9(4-11(8)16)13-5-10-14(19-7-24(20,21)22)17-6-18-15(10)25-13/h3-6H,7H2,1-2H3,(H,17,18,19)(H2,20,21,22)
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Article
PubMed
n/an/a 8.80E+3n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His-tagged human recombinant FPPS expressed in Escherichia coli BL21 (DE3) using GPP and [3H]-IPP as substrate preincubated ...

J Med Chem 60: 2119-2134 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01888
BindingDB Entry DOI: 10.7270/Q23F4RXR
More data for this
Ligand-Target Pair