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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50238068   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50238068
PNG
(CHEMBL4088735)
Show SMILES CC(O)Cn1cc2nccc(Nc3cc(ncc3C)-c3cc(F)ccc3F)c2n1
Show InChI InChI=1S/C21H19F2N5O/c1-12-9-25-19(15-7-14(22)3-4-16(15)23)8-18(12)26-17-5-6-24-20-11-28(10-13(2)29)27-21(17)20/h3-9,11,13,29H,10H2,1-2H3,(H,25,26)
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MMDB

UniProtKB/SwissProt

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UniChem

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Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal GST tagged human ALK5 (200 to 503 residues) expressed in baculovirus expression system using FAM-NH2-KVLTQMGSPSI...

Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair