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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50239666   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycine hydroxymethyltransferase


(Plasmodium falciparum)		BDBM50239666
PNG
(CHEMBL4094249)
Show SMILES COc1ccc(s1)-c1cc(cc(c1)C1(C(C)C)c2c(C)[nH]nc2OC(N)=C1C#N)C#N |c:28|
Show InChI InChI=1S/C23H21N5O2S/c1-12(2)23(17(11-25)21(26)30-22-20(23)13(3)27-28-22)16-8-14(10-24)7-15(9-16)18-5-6-19(29-4)31-18/h5-9,12H,26H2,1-4H3,(H,27,28)
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Patents

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Article
PubMed
n/an/a 323n/an/an/an/an/an/a



Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assay

J Med Chem 60: 4840-4860 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00008
BindingDB Entry DOI: 10.7270/Q2959KPJ
More data for this
Ligand-Target Pair