Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50240783 (1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Polit£cnico Nacional (IPN) Curated by ChEMBL | Assay Description Inhibition of human HMG-CoA reductase after 30 mins | Bioorg Med Chem 22: 5871-82 (2014) Article DOI: 10.1016/j.bmc.2014.09.022 BindingDB Entry DOI: 10.7270/Q2833TM8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50240783 (1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Polit£cnico Nacional (IPN) Curated by ChEMBL | Assay Description Inhibition of human HMG-CoA reductase activity using NADPH by spectrophotometrically | Bioorg Med Chem 22: 5871-82 (2014) Article DOI: 10.1016/j.bmc.2014.09.022 BindingDB Entry DOI: 10.7270/Q2833TM8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50240783 (1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Toyama Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human liver microsome CYP2D6 in assessed as [14C]formaldehyde formation | J Nat Prod 68: 64-8 (2005) Article DOI: 10.1021/np0401765 BindingDB Entry DOI: 10.7270/Q26M37Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Schizosaccharomyces pombe) | BDBM50240783 (1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.49E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Polit£cnico Nacional (IPN) Curated by ChEMBL | Assay Description Inhibition of Schizosaccharomyces pombe HMG-CoA reductase by spectrophotometry | Bioorg Med Chem 18: 4238-48 (2010) Article DOI: 10.1016/j.bmc.2010.04.096 BindingDB Entry DOI: 10.7270/Q2KW5H0Z | |||||||||||
More data for this Ligand-Target Pair |