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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50240878   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50240878
PNG
(CHEMBL4096663)
Show SMILES Cc1cccc(COc2cc(=O)n3cc(Oc4cccnc4)ccc3n2)n1
Show InChI InChI=1S/C20H16N4O3/c1-14-4-2-5-15(22-14)13-26-19-10-20(25)24-12-17(7-8-18(24)23-19)27-16-6-3-9-21-11-16/h2-12H,13H2,1H3
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 48n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Negative allosteric modulation of rat mGlu5 expressed in HEK293 cells assessed as inhibition of glutamate-induced intracellular calcium accumulation ...

J Med Chem 60: 7764-7780 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00604
BindingDB Entry DOI: 10.7270/Q2DJ5HS8
More data for this
Ligand-Target Pair