Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM50243726 ((7R,9S)-7-(((3S,4R)-3-methyl-4-o-tolylpiperidin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Antagonist activity at human ORL1 expressed in CHO cells assessed as effect on nociceptin-induced GTPgammaS binding | J Med Chem 51: 4021-9 (2008) Article DOI: 10.1021/jm701590h BindingDB Entry DOI: 10.7270/Q2KW5FTW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50243726 ((7R,9S)-7-(((3S,4R)-3-methyl-4-o-tolylpiperidin-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Displacement of [35S]MK499 from human ERG K+ channel expressed in HEK293 cells | J Med Chem 51: 4021-9 (2008) Article DOI: 10.1021/jm701590h BindingDB Entry DOI: 10.7270/Q2KW5FTW | |||||||||||
More data for this Ligand-Target Pair |