Found 6 hits of ic50 for monomerid = 50246621 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50246621
(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)Show SMILES CC1(C)CC[C@]2(CCCCC(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:17| Show InChI InChI=1S/C34H56O3/c1-29(2)18-20-34(15-9-8-10-28(36)37)21-19-32(6)23(24(34)22-29)11-12-26-31(5)16-14-27(35)30(3,4)25(31)13-17-33(26,32)7/h11,24-27,35H,8-10,12-22H2,1-7H3,(H,36,37)/t24-,25-,26+,27-,31-,32+,33+,34+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of TCPTP (unknown origin) by pNPP assay |
Bioorg Med Chem 16: 8697-705 (2008)
Article DOI: 10.1016/j.bmc.2008.07.080
BindingDB Entry DOI: 10.7270/Q2HX1CH7 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50246621
(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)Show SMILES CC1(C)CC[C@]2(CCCCC(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:17| Show InChI InChI=1S/C34H56O3/c1-29(2)18-20-34(15-9-8-10-28(36)37)21-19-32(6)23(24(34)22-29)11-12-26-31(5)16-14-27(35)30(3,4)25(31)13-17-33(26,32)7/h11,24-27,35H,8-10,12-22H2,1-7H3,(H,36,37)/t24-,25-,26+,27-,31-,32+,33+,34+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of PTP1B (unknown origin) by pNPP assay |
Bioorg Med Chem 16: 8697-705 (2008)
Article DOI: 10.1016/j.bmc.2008.07.080
BindingDB Entry DOI: 10.7270/Q2HX1CH7 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 6
(Homo sapiens (Human)) | BDBM50246621
(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)Show SMILES CC1(C)CC[C@]2(CCCCC(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:17| Show InChI InChI=1S/C34H56O3/c1-29(2)18-20-34(15-9-8-10-28(36)37)21-19-32(6)23(24(34)22-29)11-12-26-31(5)16-14-27(35)30(3,4)25(31)13-17-33(26,32)7/h11,24-27,35H,8-10,12-22H2,1-7H3,(H,36,37)/t24-,25-,26+,27-,31-,32+,33+,34+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant SHP1 |
Bioorg Med Chem 16: 8697-705 (2008)
Article DOI: 10.1016/j.bmc.2008.07.080
BindingDB Entry DOI: 10.7270/Q2HX1CH7 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase epsilon
(Homo sapiens (Human)) | BDBM50246621
(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)Show SMILES CC1(C)CC[C@]2(CCCCC(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:17| Show InChI InChI=1S/C34H56O3/c1-29(2)18-20-34(15-9-8-10-28(36)37)21-19-32(6)23(24(34)22-29)11-12-26-31(5)16-14-27(35)30(3,4)25(31)13-17-33(26,32)7/h11,24-27,35H,8-10,12-22H2,1-7H3,(H,36,37)/t24-,25-,26+,27-,31-,32+,33+,34+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PTPepsilon |
Bioorg Med Chem 16: 8697-705 (2008)
Article DOI: 10.1016/j.bmc.2008.07.080
BindingDB Entry DOI: 10.7270/Q2HX1CH7 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase F
(Homo sapiens (Human)) | BDBM50246621
(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)Show SMILES CC1(C)CC[C@]2(CCCCC(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:17| Show InChI InChI=1S/C34H56O3/c1-29(2)18-20-34(15-9-8-10-28(36)37)21-19-32(6)23(24(34)22-29)11-12-26-31(5)16-14-27(35)30(3,4)25(31)13-17-33(26,32)7/h11,24-27,35H,8-10,12-22H2,1-7H3,(H,36,37)/t24-,25-,26+,27-,31-,32+,33+,34+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant LAR |
Bioorg Med Chem 16: 8697-705 (2008)
Article DOI: 10.1016/j.bmc.2008.07.080
BindingDB Entry DOI: 10.7270/Q2HX1CH7 |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein phosphatase alpha
(Homo sapiens (Human)) | BDBM50246621
(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy...)Show SMILES CC1(C)CC[C@]2(CCCCC(O)=O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:17| Show InChI InChI=1S/C34H56O3/c1-29(2)18-20-34(15-9-8-10-28(36)37)21-19-32(6)23(24(34)22-29)11-12-26-31(5)16-14-27(35)30(3,4)25(31)13-17-33(26,32)7/h11,24-27,35H,8-10,12-22H2,1-7H3,(H,36,37)/t24-,25-,26+,27-,31-,32+,33+,34+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PTPalpha |
Bioorg Med Chem 16: 8697-705 (2008)
Article DOI: 10.1016/j.bmc.2008.07.080
BindingDB Entry DOI: 10.7270/Q2HX1CH7 |
More data for this
Ligand-Target Pair | |
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