Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trifunctional purine biosynthetic protein adenosine-3 (Homo sapiens (Human)) | BDBM50249953 (CHEMBL491129 | N-{4-[5-(2-Amino-4-oxo-3,4-dihydrot...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibition of GARFTase in human KB cells assessed as inhibition of incorporation of [14C]glycine into [14C]formyl GAR after 30 mins in presence of az... | J Med Chem 52: 2940-51 (2009) Article DOI: 10.1021/jm8011323 BindingDB Entry DOI: 10.7270/Q2NG4QH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trifunctional purine biosynthetic protein adenosine-3 (Mus musculus) | BDBM50249953 (CHEMBL491129 | N-{4-[5-(2-Amino-4-oxo-3,4-dihydrot...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibition of mouse recombinant GARFTase | J Med Chem 52: 2940-51 (2009) Article DOI: 10.1021/jm8011323 BindingDB Entry DOI: 10.7270/Q2NG4QH8 | |||||||||||
More data for this Ligand-Target Pair |