Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50265086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50265086 ((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...) Show SMILES CSc1ccc(CNC2CCN(C)CC2NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1 Show InChI InChI=1S/C24H30F3N5O2S/c1-32-10-9-20(29-12-15-3-6-17(35-2)7-4-15)21(14-32)31-22(33)13-30-23(34)18-11-16(24(25,26)27)5-8-19(18)28/h3-8,11,20-21,29H,9-10,12-14,28H2,1-2H3,(H,30,34)(H,31,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of radiolabeled MCP1 from CCR2 in human PBMC by millipore filter plate assay				Bioorg Med Chem Lett 18: 5063-5 (2008) Article DOI: 10.1016/j.bmcl.2008.07.123 BindingDB Entry DOI: 10.7270/Q23N236S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50265086 ((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...) Show SMILES CSc1ccc(CNC2CCN(C)CC2NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1 Show InChI InChI=1S/C24H30F3N5O2S/c1-32-10-9-20(29-12-15-3-6-17(35-2)7-4-15)21(14-32)31-22(33)13-30-23(34)18-11-16(24(25,26)27)5-8-19(18)28/h3-8,11,20-21,29H,9-10,12-14,28H2,1-2H3,(H,30,34)(H,31,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate assay				Bioorg Med Chem Lett 18: 5063-5 (2008) Article DOI: 10.1016/j.bmcl.2008.07.123 BindingDB Entry DOI: 10.7270/Q23N236S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50265086 ((+/-)-2-amino-N-(2-(1-methyl-4-(4-(methylthio)benz...) Show SMILES CSc1ccc(CNC2CCN(C)CC2NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1 Show InChI InChI=1S/C24H30F3N5O2S/c1-32-10-9-20(29-12-15-3-6-17(35-2)7-4-15)21(14-32)31-22(33)13-30-23(34)18-11-16(24(25,26)27)5-8-19(18)28/h3-8,11,20-21,29H,9-10,12-14,28H2,1-2H3,(H,30,34)(H,31,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxis				Bioorg Med Chem Lett 18: 5063-5 (2008) Article DOI: 10.1016/j.bmcl.2008.07.123 BindingDB Entry DOI: 10.7270/Q23N236S
					More data for this Ligand-Target Pair