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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50265849   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50265849
PNG
(2-(dimethylamino)-1-(7-(4-(indolin-1-yl)-7H-pyrrol...)
Show SMILES COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc1nc(N2CCc3ccccc23)c2cc[nH]c2n1
Show InChI InChI=1S/C28H31N7O2/c1-33(2)17-25(36)34-13-6-8-19-15-24(37-3)21(16-23(19)34)30-28-31-26-20(10-12-29-26)27(32-28)35-14-11-18-7-4-5-9-22(18)35/h4-5,7,9-10,12,15-16H,6,8,11,13-14,17H2,1-3H3,(H2,29,30,31,32)
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PC cid
PC sid
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Article
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n/an/a 0.5n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of IGF1R


Bioorg Med Chem Lett 19: 373-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.065
BindingDB Entry DOI: 10.7270/Q2F190PC
More data for this
Ligand-Target Pair
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))
BDBM50265849
PNG
(2-(dimethylamino)-1-(7-(4-(indolin-1-yl)-7H-pyrrol...)
Show SMILES COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc1nc(N2CCc3ccccc23)c2cc[nH]c2n1
Show InChI InChI=1S/C28H31N7O2/c1-33(2)17-25(36)34-13-6-8-19-15-24(37-3)21(16-23(19)34)30-28-31-26-20(10-12-29-26)27(32-28)35-14-11-18-7-4-5-9-22(18)35/h4-5,7,9-10,12,15-16H,6,8,11,13-14,17H2,1-3H3,(H2,29,30,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of IGF1R phosphorylation by cellular assay


Bioorg Med Chem Lett 19: 373-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.065
BindingDB Entry DOI: 10.7270/Q2F190PC
More data for this
Ligand-Target Pair