Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 50265967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50265967 (CHEMBL4079515) Show SMILES Cn1c2CCNC(=O)c2cc1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C17H21N5O2/c1-22-14-3-7-18-16(23)12(14)10-15(22)13-2-6-19-17(21-13)20-11-4-8-24-9-5-11/h2,6,10-11H,3-5,7-9H2,1H3,(H,18,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) in the presence of 60 uM ATP				J Med Chem 60: 3438-3450 (2017) Article DOI: 10.1021/acs.jmedchem.7b00267 BindingDB Entry DOI: 10.7270/Q2FJ2K8J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50265967 (CHEMBL4079515) Show SMILES Cn1c2CCNC(=O)c2cc1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C17H21N5O2/c1-22-14-3-7-18-16(23)12(14)10-15(22)13-2-6-19-17(21-13)20-11-4-8-24-9-5-11/h2,6,10-11H,3-5,7-9H2,1H3,(H,18,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) in the presence of 1 mM ATP				J Med Chem 60: 3438-3450 (2017) Article DOI: 10.1021/acs.jmedchem.7b00267 BindingDB Entry DOI: 10.7270/Q2FJ2K8J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50265967 (CHEMBL4079515) Show SMILES Cn1c2CCNC(=O)c2cc1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C17H21N5O2/c1-22-14-3-7-18-16(23)12(14)10-15(22)13-2-6-19-17(21-13)20-11-4-8-24-9-5-11/h2,6,10-11H,3-5,7-9H2,1H3,(H,18,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated RSK levels				J Med Chem 60: 3438-3450 (2017) Article DOI: 10.1021/acs.jmedchem.7b00267 BindingDB Entry DOI: 10.7270/Q2FJ2K8J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50265967 (CHEMBL4079515) Show SMILES Cn1c2CCNC(=O)c2cc1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C17H21N5O2/c1-22-14-3-7-18-16(23)12(14)10-15(22)13-2-6-19-17(21-13)20-11-4-8-24-9-5-11/h2,6,10-11H,3-5,7-9H2,1H3,(H,18,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated ERK2 levels				J Med Chem 60: 3438-3450 (2017) Article DOI: 10.1021/acs.jmedchem.7b00267 BindingDB Entry DOI: 10.7270/Q2FJ2K8J
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50265967 (CHEMBL4079515) Show SMILES Cn1c2CCNC(=O)c2cc1-c1ccnc(NC2CCOCC2)n1 Show InChI InChI=1S/C17H21N5O2/c1-22-14-3-7-18-16(23)12(14)10-15(22)13-2-6-19-17(21-13)20-11-4-8-24-9-5-11/h2,6,10-11H,3-5,7-9H2,1H3,(H,18,23)(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of MEK1 (unknown origin)				J Med Chem 60: 3438-3450 (2017) Article DOI: 10.1021/acs.jmedchem.7b00267 BindingDB Entry DOI: 10.7270/Q2FJ2K8J
					More data for this Ligand-Target Pair