Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene B4 receptor 1 (Homo sapiens (Human)) | BDBM50291511 (2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]-LTB4 from isolated neutrophils | Bioorg Med Chem Lett 7: 949-954 (1997) Article DOI: 10.1016/S0960-894X(97)00134-0 BindingDB Entry DOI: 10.7270/Q25D8RW3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily M member 2 (Homo sapiens (Human)) | BDBM50291511 (2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiology | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02129 BindingDB Entry DOI: 10.7270/Q2HT2T5G | |||||||||||
More data for this Ligand-Target Pair |